from Houston Public Media by Carrie Feibel MD Anderson launched “Moon Shots” in 2012 with the aim of speeding up the movement of basic discoveries from the laboratory to the actual cancer patient. This year, six new cancers have been ...
Read More »Pancreatic cancer-related miRNAs can be transferred to dendritic cells via exosome and inhibit target mRNA expression
It has been reported tumor-derived exosomes can transfer miRNAs to recipient cells in the tumor microenvironment, promoting tumor invasion and metastasis. The present research aimed to explore how pancreatic cancer (PC) derived exosomal miRNAs inhibited mRNA expression of dendritic cells ...
Read More »Blood test holds great promise for early detection of pancreatic cancer
from Medical News Today by Catharine Paddock PhD A study that successfully differentiated patients with pancreatic cancer from those with another pancreatic disease using a new biomarker, could lead to a blood test that detects pancreatic cancer early enough for ...
Read More »Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
Pancreatic ductal adenocarcinomas (PDACs) are highly metastatic with poor prognosis, mainly due to delayed detection. We hypothesized that intercellular communication is critical for metastatic progression. Here, researchers from the Weill Cornell Medical College show that PDAC-derived exosomes induce liver pre-metastatic ...
Read More »On-chip detection of exosomal RNA for cancer study and diagnosis
There has been increasing evidence that micro and messenger RNA derived from exosomes play important roles in pancreatic and other cancers. In this work, researchers from the University of Notre Dame present a microfluidics-based approach to the analysis of exosomal RNA ...
Read More »Pancreatic Cancer-Associated Diabetes Is an “Exosomopathy”
Diabetes may be a consequence of pancreatic cancer, preceding cancer diagnosis. The underlying mechanism is the release exosomes delivering adrenomedullin to β-cells, inducing endoplasmic reticulum stress and perturbations in the unfolded protein response, leading to β-cell dysfunction and death. This ...
Read More »Aethlon Medical and Exosome Sciences Announce the Advancement of a Broad-Spectrum Cancer Detection and Monitoring Platform
SAN DIEGO and PRINCETON, N.J., Sept. 8, 2014 /PRNewswire/ — Aethlon Medical, Inc. (NASDAQ: OTCQB:AEMD), and its diagnostic subsidiary, Exosome Sciences, Inc. (ESI), announced today that ESI researchers have developed and initially validated a lectin-based diagnostic platform that is able to ...
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