Engineered extracellular vesicles carrying PD-L1 and miR-27a-3p restore T cell balance in IBD models, reducing inflammation while preserving epithelial integrity in inflamed intestinal tissue...
Read More »A new immune evasion pathway in cancer reveals statins as immunotherapy boosters
Tumors use extracellular vesicles to export immunosuppressive PD-L1, limiting immunotherapy response, while statins emerge as a practical way...
Read More »Inhalable bispecific exosomes reprogram the tumor environment in resistant melanoma
Engineered extracellular vesicles deliver dual immune targeting to lung metastases, activating T cells and overcoming resistance to checkpoint...
Read More »Extracellular vesicles in follicular fluid reveal immune-regulating PD-L1 subpopulations linked to fertility
Extracellular vesicles carrying PD-L1 in follicular fluid may regulate immune tolerance and serve as potential biomarkers for fertility assessment and...
Read More »Aethlon Medical’s Hemopurifier® shows Changes in Extracellular Vesicles, Extracellular MicroRNAs, and T Cell Numbers in Australian Oncology Clinical Trial
Aethlon Medical reported early findings from its Australian oncology trial showing directional changes in extracellular vesicles, exosomes, microRNAs, and lymphocyte counts following Hemopurifier treatment in patients resistant to anti-PD-1 therapy...
Read More »Dual-marker approach for precise detection of breast cancer-derived exosomes using aptamers and FRET
Breast cancer is one of the most common cancers worldwide, and detecting it early is crucial for better treatment planning and improving patient outcomes. Researchers at the Beijing Institute of Technology...
Read More »Cancer exports molecular ‘saboteurs’ to remotely disarm immune system
Discovery May Help Explain Immunotherapy Resistance, Hints at New Therapies Immunotherapy drugs known as checkpoint inhibitors have revolutionized cancer treatment: many patients with malignancies that until recently would have been considered untreatable are experiencing long-term remissions. But the majority of ...
Read More »Cancer cells use exosomes to put the brakes on immune system
In order for cancer cells to successfully spread and multiply, they must find a way to avoid the body’s own immune system. Scientists at the German Cancer Research Center (DKFZ) have published an explanation for how this occurs with chronic ...
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