Emerging advances in extracellular vesicle (EV) research brings along new promises for tailoring clinical treatments in order to meet specific disease features of each patient in a personalized medicine...
Read More »Extracellular vesicles could be personalized drug delivery vehicles
Creating enough nanovesicles to inexpensively serve as a drug delivery system may be as simple as putting the cells through a sieve, according to an international team of researchers who used mouse autologous — their own — immune cells to ...
Read More »Microfluidics for exosome isolation and analysis – enabling liquid biopsy for personalized medicine
Exosomes, the smallest sized extracellular vesicles (∽30-150 nm) packaged with lipids, proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their cells of origin, have emerged as key players in intercellular communication. Their presence in bodily fluids, where they ...
Read More »Liquid biopsy – a step forward towards precision medicine in urologic malignancies
There is a growing trend towards exploring the use of a minimally invasive “liquid biopsy” to identify biomarkers in a number of cancers, including urologic malignancies. Multiple aspects can be assessed in circulating cell-free DNA, including cell-free DNA levels, integrity, ...
Read More »Liquid Biopsy for Cancer – Circulating Tumor Cells, Circulating Free DNA or Exosomes?
Precision medicine and personalized medicine are based on the development of biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry information on tumor development and progression. Compared with traditional ‘solid biopsy’, which cannot always ...
Read More »Introduction to exosomes and other extracellular vesicles – Implications for personalized and precision medicine
Rey Magana – A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based on this discovery promise to become important tools ...
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