Researchers have unlocked mysteries surrounding how a pregnant mother’s cells and her fetus’ cells communicate throughout pregnancy. With this new information, The University of Texas Medical Branch at Galveston team and their colleagues in South...
Read More »Featured Exosome Job – Senior Research Associate-Stem Cell Biology
Celularity is NJ-based biotechnology start-up company striving to become the leader in cellular therapeutics. We are looking for a highly motivated research associate scientist to a group of researchers evaluating novel cell therapies in the field of stem...
Read More »Placental exosomes as early biomarker of preeclampsia
There is a need to develop strategies for early prediction of patients who will develop preeclampsia (PE), in order to establish preventive strategies to reduce the prevalence and severity of the disease and their associated complications. The objective of this ...
Read More »UTMB researchers show signals carried by exosomes trigger labor and delivery
UTMB researchers learn more about signals that prompt labor and delivery to better understand what triggers preterm delivery. GALVESTON, Texas – In a normal full-term pregnancy, signals from the mature organs of the fetus and the aging placental membranes and ...
Read More »Potential implications of embryonic-maternal cross-talk via exosomes
A myriad of locally produced factors into the microenvironment of the reproductive tract is regulated, not one-way but rather, through embryonic-maternal cross-talk. In this mini-review, the authors focused on the exosomes, which are cell-derived vesicles of 30-100 nm in diameter, ...
Read More »A New Assay to Quantify Syncytiotrophoblast Extracellular Vesicles in Biological Fluids
The pregnancy-associated disease preeclampsia is related to the release of syncytiotrophoblast extracellular vesicles (STBEV) by the placenta. To improve functional research on STBEV, reliable and specific methods are needed to quantify them. However, only a few quantification methods are available ...
Read More »Placenta-Derived Exosomes and their Role in Human Reproduction
The syncytiotrophoblast (STB) of human placenta constitutively produces and secretes extracellular vesicles of different size, morphology and function that enter the maternal circulation, and participate in the maternal-fetal cross-talk during pregnancy. Syncytiotrophoblast-derived microvesicles/microparticles (STBM) are larger microvesicles (0.2-2 μm) shed ...
Read More »Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy
Human placenta releases specific nanovesicles (i.e. exosomes) into the maternal circulation during pregnancy, however, the presence of placenta-derived exosomes in maternal blood during early pregnancy remains to be established. The aim of this study was to characterize gestational age related ...
Read More »