Sensitization to human leukocyte antigens (HLA) remains a significant immunologic barrier to successful transplantation. Identifying immune mechanisms responsible for antibody-mediated rejection (ABMR) is an important goal. Here researchers at Cedars-Sinai Medical Center explored the possibility of predicting the risk for ...
Read More »Delivery of Small Interfering RNAs to Cells via Exosomes
Exosomes are small membrane bound vesicles between 30 and 100 nm in diameter of endocytic origin that are secreted into the extracellular environment by many different cell types. Exosomes play a role in intercellular communication by transferring proteins, lipids, and ...
Read More »Detection of exosomal prions in blood by immunochemistry techniques
In most forms of prion diseases blood is infectious, but the detection by immunochemistry techniques of the only available marker of infection (the misfolded prion protein, PrPTSE) in blood remains elusive. Researchers at the Istituto Superiore di Sanità, Italy developed ...
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