Tag Archives: plasma

Exosomes play important roles in cancer progression. Although its contents (e.g., proteins and microRNAs) have been focused on in cancer research, particularly as potential diagnostic markers, the exosome behavior and methods for exosome quantification remain unclear. In the present study, ...

Exosomes are cell-secreted nanovesicles (40-200 nm) that represent a rich source of novel biomarkers in the diagnosis and prognosis of certain diseases. Despite the increasingly recognized relevance of these vesicles as biomarkers, their detection has been limited due in part ...

from BiotechDaily International –  Neurological disease researchers have developed a method for using a biomarker in the blood to predict the likelihood of mild cognitive impairment (MCI) progressing into full-blown Alzheimer’s disease (AD). “MCI is often a transitional stage between ...

Ovarian cancer is the leading cause of death among gynecologic malignancies. Since ovarian cancer develops asymptomatically, it is often diagnosed at an advanced and incurable stage. Despite many years of research, there is still a lack of reliable diagnostic markers ...

CAMBRIDGE, Mass.–(BUSINESS WIRE)–Exosome Diagnostics, Inc., the world’s only provider of a revolutionary liquid biopsy platform that enables analysis of both living and dying processes of disease states, thus aiming to reduce or eliminate the need for tissue biopsies, today announced ...

There is growing appreciation for the importance of non-protein-coding genes in development and disease. Although much is known about microRNAs, limitations in bioinformatic analyses of RNA sequencing have precluded broad assessment of other forms of small-RNAs in humans. By analysing ...

In the last decades, several studies demonstrated that the tumor microenvironment is a critical determinant not only of tumor progression and metastasis, but also of resistance to therapy. Exosomes are small membrane vesicles of endocytic origin, which contain mRNAs, DNA ...

Exosome Diagnostics recently announced the launch of ExoDx Lung(ALK), a liquid biopsy platform that allows for non-invasive detection of biomarkers and potentially negates the need for a tissue biopsy. The test analyzes exosomal RNA from a blood or urine sample and ...

Extracellular vesicles, including exosomes, are nanoscale vesicles that carry molecular information of parental cells. They are being pursued as biomarkers of cancers that are difficult to detect or serially follow. Here researchers from Massachusetts General Hospital present a compact sensor ...

Exosomes are emerging targets for biomedical research. However, suitable methods for the isolation of blood plasma-derived exosomes without impurities have not yet been described. Therefore, researchers from Semmelweis University, Hungary investigated the efficiency and purity of exosomes isolated with potentially ...