Tag Archives: plasma

RNA-seq for blood-based pan-cancer diagnostics

exosomes

from Nature Reviews Genetics by Liesbet Lieben A systemic, minimally invasive diagnostic test to determine whether an individual has cancer could greatly improve cancer prognosis by facilitating early diagnosis and improving monitoring. However, the use of blood-based ‘liquid biopsies’ is ...

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Plasma EGFR mutation detection using a combined exosomal RNA and circulating tumor DNA approach in patients with acquired resistance to first-generation EGFR-TKIs

exosome rna

Presented at the AACR-NCI-EORTC conference. After initial responses to tyrosine kinase inhibitors (TKIs), NSCLC patients harboring EGFR activating mutations inevitably progress, with the “gatekeeper” EGFR T790M resistance mutation accounting for approximately 60% of cases of acquired resistance (AR) to TKIs. ...

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Grazing Affects Exosomal Circulating MicroRNAs in Cattle

exosome rna

Circulating microRNAs (c-miRNAs) are associated with physiological adaptation to acute and chronic aerobic exercise in humans. To investigate the potential effect of grazing movement on miRNA circulation in cattle, here researchers from the National Institute of Livestock and Grassland Science, Japan ...

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