Researchers from the Chengdu University of Traditional Chinese Medicine set out to assess a new and highly specific, but low-cost, easily performed and suitable for large-scale applications method...
Read More »Isolation of exosomes with polyethylene glycol from cell culture supernatant for in-depth proteome profiling
Exosomes are secreted nanovesicles shed by almost all kinds of cells. Recently, increased interest has been focused on these extracellular vesicles as natural carriers transporting biological contents for intercellular communication. However, current isolation techniques, such as ultracentrifugation, are not convenient ...
Read More »ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles
Initially thought to be a means for cells to eliminate waste, secreted extracellular vesicles, known as exosomes, are now understood to mediate numerous healthy and pathological processes. Though abundant in biological fluids, purifying exosomes has been challenging because their biophysical ...
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