Precision medicine for cancer patients aims to adopt the most suitable treatment options during diagnosis and treatment of individuals. Detecting circulating tumor cell (CTC) or circulating tumor DNA (ctDNA) in plasma or serum could serve as liquid biopsy, which would ...
Read More »Liquid biopsy – a step forward towards precision medicine in urologic malignancies
There is a growing trend towards exploring the use of a minimally invasive “liquid biopsy” to identify biomarkers in a number of cancers, including urologic malignancies. Multiple aspects can be assessed in circulating cell-free DNA, including cell-free DNA levels, integrity, ...
Read More »Emerging concepts in liquid biopsies
Characterizing and monitoring tumor genomes with blood samples could achieve significant improvements in precision medicine. As tumors shed parts of themselves into the circulation, analyses of circulating tumor cells, circulating tumor DNA, and tumor-derived exosomes, often referred to as “liquid ...
Read More »Liquid Biopsy for Cancer – Circulating Tumor Cells, Circulating Free DNA or Exosomes?
Precision medicine and personalized medicine are based on the development of biomarkers, and liquid biopsy has been reported to be able to detect biomarkers that carry information on tumor development and progression. Compared with traditional ‘solid biopsy’, which cannot always ...
Read More »Featured Exosome Job – VP, Global HD-Translational Precision Oncology
Job ID 199898BR Posting Title VP, Global HD-Translational Precision Oncology COE-(TPO-CoE) Division PHARMA Business Unit ONCOLOGY BU – NPH Country USA Work Location East Hanover, NJ Company/Legal Entity Novartis Pharmaceuticals Functional Area Research & Development Job Type Full Time Employment ...
Read More »IBM researchers target exosomes with their lab-on-chip technology to overcome challenges in liquid biopsies
IBM scientists will collaborate with the Icahn School of Medicine at Mount Sinai to test on prostate cancer IBM (NYSE: IBM) scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale ...
Read More »Microfluidic Exosome Analysis – toward Liquid Biopsy for Cancer
Tissue biopsy is often required for cancer diagnosis and prognosis. However, tissue biopsy is highly invasive for most primary tumors and metastatic diseases, especially brain cancer, lung cancer, and ovarian cancer, which require difficult surgeries. The obtained tissue quality and ...
Read More »Introduction to exosomes and other extracellular vesicles – Implications for personalized and precision medicine
Rey Magana – A recently discovered communication system used by cells to send messages across the human body promises to revolutionize our understanding of disease and how we treat it. Technologies based on this discovery promise to become important tools ...
Read More »Biobanking of Exosomes in the Era of Precision Medicine
The emergence of personalized medicine demands high-quality human biospecimens with appropriate clinical annotation, especially in complex diseases such as cancer, neurodegenerative, cardiovascular, and metabolic alterations in which specimen heterogeneity and individual responses often complicate the development of precision therapeutic programs. ...
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