A $10.4 million ARPA-H grant is supporting development of rapid maternal blood tests using extracellular vesicles and other biomarkers to identify fetuses at risk of low oxygen during labor...
Read More »Maternal weight may influence microbiota signalling in amniotic fluid
Extracellular vesicles produced by the maternal microbiota were detected in gut and amniotic fluid samples, suggesting microbial signaling may...
Read More »Scientists unlock secrets of maternal/fetal cellular communication during pregnancy
Researchers have unlocked mysteries surrounding how a pregnant mother’s cells and her fetus’ cells communicate throughout pregnancy. With this new information, The University of Texas Medical Branch at Galveston team and their colleagues in South...
Read More »UTMB researchers show signals carried by exosomes trigger labor and delivery
UTMB researchers learn more about signals that prompt labor and delivery to better understand what triggers preterm delivery. GALVESTON, Texas – In a normal full-term pregnancy, signals from the mature organs of the fetus and the aging placental membranes and ...
Read More »A New Assay to Quantify Syncytiotrophoblast Extracellular Vesicles in Biological Fluids
The pregnancy-associated disease preeclampsia is related to the release of syncytiotrophoblast extracellular vesicles (STBEV) by the placenta. To improve functional research on STBEV, reliable and specific methods are needed to quantify them. However, only a few quantification methods are available ...
Read More »Placenta-Derived Exosomes and their Role in Human Reproduction
The syncytiotrophoblast (STB) of human placenta constitutively produces and secretes extracellular vesicles of different size, morphology and function that enter the maternal circulation, and participate in the maternal-fetal cross-talk during pregnancy. Syncytiotrophoblast-derived microvesicles/microparticles (STBM) are larger microvesicles (0.2-2 μm) shed ...
Read More »Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy
Human placenta releases specific nanovesicles (i.e. exosomes) into the maternal circulation during pregnancy, however, the presence of placenta-derived exosomes in maternal blood during early pregnancy remains to be established. The aim of this study was to characterize gestational age related ...
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