Extracellular vesicles (EVs) are small membrane-bound organelles naturally released from cells and potentially function as vehicles of intercellular communication. Cells release numerous sub-species of EVs, including exosomes and microvesicles, which are formed via distinct cellular pathways and molecular machineries and ...
Read More »A hybridization chain reaction based assay for fluorometric determination of exosomes
Exosomes represent a new generation of biomarkers for the early diagnosis of hepatic carcinoma. Researchers from Tongji Medical College have developed a fluorometric assay that is based on the hybridization chain reaction and magnetic...
Read More »Microfluidics-based on-a-chip systems for isolating and analysing extracellular vesicles
Extracellular vesicles (EVs), which can be found in almost all body fluids, consist of a lipid bilayer enclosing proteins and nucleic acids from their...
Read More »Protein cancer biomarkers in circulating exosomes
Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be traced to the cells from which they originated, reflecting the ...
Read More »Exosomes in ovarian cancer
Exosomes are nanoparticles(40-100 nm) secreted by most cells in the body, which can be isolated from several types of extracellular fluids. It has been shown that exosomes play a key role in intercellular communication and in transportation of genetic information. ...
Read More »Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
Developing blood-based tests is appealing for non-invasive disease diagnosis, especially when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes have attracted increasing interest in non-invasive cancer diagnosis and monitoring of treatment response. However, the biology and ...
Read More »