Biomarker detection for disease diagnosis, prognosis, and therapeutic response is becoming increasingly reliable and accessible. Particularly, the identification of circulating cell-free chemical and biochemical substances, cellular and subcellular entities...
Read More »Proteomic and post-translational modification profiling of exosome-mimetic nanovesicles compared to exosomes
Issues associated with upscaling exosome production for therapeutic use may be overcome through utilizing artificial exosomes. Cell-derived mimetic nanovesicles (M-NVs) are a potentially...
Read More »Boosting the biogenesis and secretion of mesenchymal stem cell-derived exosomes
A limitation of using exosomes to their fullest potential is their limited secretion from cells, a major bottleneck to efficient exosome production and...
Read More »Unravelling the proteomic landscape of extracellular vesicles in prostate cancer by density-based fractionation of urine
Extracellular vesicles (EV) are increasingly being recognized as important vehicles of intercellular communication and promising diagnostic and prognostic biomarkers in cancer. Despite this enormous...
Read More »Seer debuts with proprietary proteomics platform to enable early detection of cancer and neurological diseases
Advancing pipeline of first-in-class liquid biopsy products with the goal of detecting diseases at early, pre-symptomatic stages Seer, Inc., launched today to capture and translate molecular insights from the...
Read More »Protein cancer biomarkers in circulating exosomes
Circulating cancer exosomes are microvesicles which originate from malignant cells and other organs influenced by the disease and can be found in blood. The exosomal proteomic cargo can often be traced to the cells from which they originated, reflecting the ...
Read More »An optimized method for enrichment of whole brain-derived extracellular vesicles reveals insight into Alzheimer’s disease
Alzheimer's disease (AD) is the major cause of dementia that has increased dramatically in prevalence over the past several decades. Yet many questions still surround the etiology of AD. Recently, extracellular vesicles (EVs) that transport protein...
Read More »Exosomics
Exosomes are biomolecular nanostructures released from cells. They carry specific biomolecular information and are mainly researched for their exquisite properties as a biomarker source and delivery system. Researchers from the Bellvitge Biomedical Research Institute introduce exosomes in the context of other ...
Read More »Tissue crosstalk via extracellular vesicles during exercise can exert systemic biological effects
Exercise stimulates the release of molecules into the circulation, supporting the concept that inter-tissue signaling proteins are important mediators of adaptations to exercise. Recognizing that many circulating proteins are packaged in extracellular vesicles...
Read More »Proteomics method to identify protein profiles in exosomes
Exosomes are membrane-bound nanovesicles that transport molecular signals (e.g., proteins) between cells and are released from a wide range of cells, including the human placenta. Interestingly...
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