Exosomes, nanosized membrane vesicles secreted by cardiac progenitor cells (Exo-CPC), inhibit cardiomyocyte apoptosis under stress conditions, promote angiogenesis in vitro, and prevent the early...
Read More »Quantification of MicroRNAs in Urine-Derived Specimens
MicroRNAs are small noncoding RNAs which regulate the expression of genes involved in a multitude of cellular processes. Dysregulation of microRNAs and-in consequence-of the affected pathways is frequently observed in numerous pathologies including cancers. Therefore, tumor-related alterations in microRNA expression ...
Read More »Small RNA analysis in exosomes provides insights into localized RNA processing, degradation and sorting
Exosomes are small vesicles that mediate cell-cell communication. They contain proteins, lipids and RNA, and evidence is accumulating that these molecules are specifically sorted for release via exosomes. Researchers from UMC Utrecht recently showed that endothelial-cell-produced exosomes promote angiogenesis in ...
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