All body fluids contain cell-derived membrane-enclosed vesicles. Such vesicles are shed by prokaryotes and eukaryotic cells and contain messages to the environment. Cell-derived vesicles are thought to contribute to homeostasis, disease development, and progression, may provide novel biomarkers, and may ...
Read More »Particle size distribution of exosomes and microvesicles
Enumeration of extracellular vesicles has clinical potential as a biomarker for disease. In biological samples, the smallest and largest vesicles typically differ 25-fold in size, 300,000-fold in concentration, 20,000-fold in volume, and 10,000,000-fold in scattered light. Due to this heterogeneity, ...
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