Tag Archives: regenerative medicine

Regenerative medicine company Exopharm Limited (ASX:EX1) announces first dosing has occurred in the PLEXOVAL Phase I study using exosomes...

Exosomes are cell-derived extracellular vesicles of 30-150nm in size and are involved in intercellular communication. Because of their bioactive cargo, consisting of proteins, RNA and lipids, and their natural ability to deliver these biomolecules to recipient...

Extracellular vesicles (EVs)-based therapeutics are based on the premise that EVs shed by stem cells exert similar therapeutic effects and these have been proposed as an alternative to cell therapies. EV-mediated delivery is an effective and efficient system of cell-to-cell ...

Aegle Therapeutics Corporation, a regenerative medicine company isolating extracellular vesicles (“EVs”) from allogeneic bone marrow derived mesenchymal stem cells (“MSCs”) to treat severe...

Extracellular vesicles, in particular the subclass exosomes, are rapidly emerging as a novel therapeutic platform. However, currently very few clinical validation studies and no clearly defined manufacturing process exist. As exosomes progress towards the clinic for treatment of a vast ...

Position Overview: Develop scalable cell culture and exosome purification processes to improve production of regenerative medicine products. Key Accountabilities / Responsibilities: Lead efforts in upstream bioprocess development, with particular focus on the efficient expansion of adherent and non-adherent cells (e.g. ...

Cardiovascular disease is a significant cause of morbidity and mortality around the world. The damaged cardiac tissue is unable to repair itself following injury warranting the development of alternate therapies. Cell therapy has emerged recently as a viable treatment option ...

Background: What’s an Exosome? Exosomes are nanosizedvesicles released by all cell types, including stem cells. Exosomes contain ‘cargo’ such as proteins, RNA and cytokines which reflect the intracellular contents of their donor cell. DrLim, and others, have found that exosome ...

United Therapeutics Research Technician – Exosomes in Research Triangle Park, North Carolina Position Overview: Conduct and assist in research efforts to develop tissue-based regenerative medicine products for the treatment of pulmonary hypertension and other lung diseases. Key Accountabilities / Responsibilities: ...

Researchers at the Medical University of Vienna previously showed that, when peripheral blood mononuclear cells (PBMCs) were stressed with ionizing radiation, they released paracrine factors that showed regenerative capacity in vitro and in vivo. This study aimed to characterize the ...