Engineered extracellular vesicles displaying antigen and cytokine signals drive antigen-specific regulatory T cell induction, offering a modular strategy to restore immune tolerance in autoimmune and allergic...
Read More »Extracellular vesicles boost production of anti-inflammatory cells to heal heart muscle after heart attacks in mice
Researchers at Cedars-Sinai used extracellular vesicles to deliver BCYRN1 RNA, enhancing regulatory T cell production in mice, reducing heart attack damage, and offering potential for treating...
Read More »Donor-derived exosomes induce specific regulatory T cells to suppress immune inflammation in the allograft heart
To inhibit the immune inflammation in the allografts can be beneficial to organ transplantation. This study aims to induce the donor antigen specific regulatory T cells (Treg cell) inhibit the immune inflammation in the allograft heart. In this study, peripheral ...
Read More »Donor-derived exosomes induce specific regulatory T cells to suppress immune inflammation
To inhibit the immune inflammation in the allografts can be beneficial to organ transplantation. This study aims to induce the donor antigen specific regulatory T cells (Treg cell) inhibit the immune inflammation in the allograft heart. In this study, peripheral ...
Read More »Regulatory T Cell-Derived Exosomes – Possible Therapeutic and Diagnostic Tools in Transplantation
Exosomes are extracellular vesicles released by many cells of the body. These small vesicles play an important part in intercellular communication both in the local environment and systemically, facilitating in the transfer of proteins, cytokines as well as miRNA between ...
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