MicroRNAs are small noncoding RNAs which regulate the expression of genes involved in a multitude of cellular processes. Dysregulation of microRNAs and-in consequence-of the affected pathways is frequently observed in numerous pathologies including cancers. Therefore, tumor-related alterations in microRNA expression ...
Read More »Surface Acoustic Wave Lysis and Ion-Exchange Membrane Quantification of Exosomal MicroRNA
MicroRNA detection and quantification are commonly explored techniques for diagnostic and prognostic predictions. Typically, microRNAs are extracted and purified from a biological source, converted into complementary DNA (cDNA), and amplified using real time polymerase chain reaction (RT-PCR). The number of ...
Read More »Norgen Biotek Launches Novel Exosome Isolation and Exosomal microRNA Purification Kits
Norgen Biotek, an innovative privately held Canadian biotechnology company focusing on advancing powerful tools for nucleic acids (NA) and protein purification, today announced the launch of novel kits for the fast and simple isolation of exosomes from...
Read More »Identification and Analysis of Circulating Exosomal microRNA in Human Body Fluids
Exosomes are 40-100 nm sized vesicles released from cells when multivesicular bodies fuse with the plasma membrane. These vesicles take part in cell-to-cell communication by binding and signalling through membrane receptors on cells or by transferring proteins, RNA, and lipids ...
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