Tag Archives: rna-seq

Extracellular vesicles (EVs) have great potential as a source for clinically relevant biomarkers since they can be readily isolated from biofluids and carry microRNA (miRNA), mRNA, and proteins that can reflect disease status. However, the biological and technical variability of ...

Scientists have improved their understanding of a new form of cell-cell communication that is based on extracellular RNA (exRNA). RNA, a molecule that...

Exosomes and other extracellular vesicles (EVs) have emerged as an important mechanism of cell-to-cell communication. However, previous studies either did not fully resolve what genetic materials were shuttled by exosomes or only focused on a specific set of...

Release of exosomes have been shown to play critical roles in drug resistance by delivering cargo. Targeting the transfer of exosomes from resistant cells to sensitive cells may be an approach to overcome some cases of drug resistance. In this ...

Recent studies have shown that circular RNAs (circRNAs) are abundant, widely expressed in mammals, and can display cell-type specific expression. However, how production of circRNAs is regulated and their precise biological function remains largely unknown. To study how circRNAs might ...

One of the newest and strongest members of intercellular communicators, the extracellular vesicles (EVs) and their enclosed RNAs; extracellular RNAs (exRNAs) have been acknowledged as putative biomarkers and therapeutic targets for various diseases. Although a very deep insight has not ...

Exosome Diagnostics, Inc. in recent partnership with Takeda Pharmaceuticals has produced the industry’s first data demonstrating the power of exosomal RNA (exoRNA) for long RNA sequencing (RNA-Seq). This discovery will enable insight into a patient’s genetic makeup that was previously ...

Exosome Diagnostics, Inc., the world’s only provider of an exosome liquid biopsy platform to monitor disease biomarkers in patient blood, with the goal of reducing or eliminating the need for tissue biopsies, has entered into a collaboration with Takeda Pharmaceuticals ...

Pancreatic cancer is one of the most lethal malignancies with a poor prognosis. Liquid biopsies are non-invasive methods for diagnostics to detect early stage cancer resulting in more successful treatment. One liquid biopsy technique is the detection of RNA from ...

RNA-seq Explorer Solution generates clear insights for cancer ‘omics’ analyses Hilden, Germany, and Germantown, Maryland, April 14, 2016 – QIAGEN N.V. (NASDAQ: QGEN; Frankfurt Prime Standard: QIA) today announced introduction of its unique RNA-seq Explorer Solution, a bioinformatics-driven approach to ...