Tag Archives: rna sequencing

The combination of single-cell transcriptomic analysis and plasma RNA sequencing represents an approach for the development of new noninvasive...

Scientists have improved their understanding of a new form of cell-cell communication that is based on extracellular RNA (exRNA). RNA, a molecule that...

Cholangiocarcinoma (CCA) is an aggressive malignancy associated with unfavorable prognosis, and it’s difficult to diagnose and no effective treatments are available. Long non-coding RNAs (lncRNAs) play important roles in tumorigenesis and metastasis. Intact lncRNAs from exosomes have sparked much interest ...

We are looking for highly motivated postdoctoral research fellows with a PhD in molecular biology and neuroscience field awarded within the past three years. These positions will be involved in functional characterization of extracellular vesicles (such as exosomes) in Alzheimer’s ...

We are looking for highly motivated postdoctoral research fellows with a PhD in molecular biology and neuroscience field awarded within the past three years. These positions will be involved in functional characterization of extracellular vesicles (such as exosomes) in Alzheimer’s ...

Exosome Diagnostics, Inc., the world’s only provider of an exosome liquid biopsy platform to monitor disease biomarkers in patient blood, with the goal of reducing or eliminating the need for tissue biopsies, has entered into a collaboration with Takeda Pharmaceuticals ...

Parkinson’s disease (PD) is a debilitating neurological disorder for which prognostic and diagnostic biomarkers are lacking. Cerebrospinal fluid (CSF) is an accessible body fluid that comes into direct contact with the central nervous system (CNS) and acts as a nuclease-free ...

Exosomes are 30-150nM membrane-bound secreted vesicles that are readily isolated from biological fluids such as urine (UEs). Exosomes contain proteins, micro RNA (miRNA), messenger RNA (mRNA), and long non-coding RNA (lncRNA) from their cells of origin. Although miRNA, protein and ...

Functional biomolecules, including small noncoding RNAs (ncRNAs), are released and transmitted between mammalian cells via extracellular vesicles (EVs), including endosome-derived exosomes. The small RNA composition in cells differs from exosomes, but underlying mechanisms have not been established. Researchers from the ...

Exosomes, endosome-derived membrane microvesicles, contain specific RNA transcripts that are thought to be involved in cell-cell communication. These RNA transcripts have great potential as disease biomarkers. To characterize exosomal RNA profiles systemically, a team led by researchers at the Medical ...