Tag Archives: saliva

Saliva contains biological information as blood and is recognized as a valuable diagnostic medium for their noninvasiveness. Although “-omics” researches have tried to investigate saliva, the origin and significance of its contents are not clear, and its usage is largely ...

from Medical News Today by Catharine Paddock PhD The news marks a milestone in over 10 years of research led by oral cancer and saliva diagnostics researcher Prof. David Wong, of the School of Dentistry at the University of California-Los ...

from The Cell Culture Dish – A guest blog by William G. Whitford, Strategic Solutions Leader, BioProcess, GE Healthcare Life Sciences Exosomes in Nature It was discovered some time ago that eukaryotic cells regularly secrete such structures as microvesicles, macromolecular ...

Aging has been defined as a progressive organic functional decline with loss of homeostasis and increasing probability of illness and death. All age-dependent diseases are connected to aging and these diseases have an influence on one another. Some of the ...

ExoQuick-TC(TM) (EQ), a chemical-based agent designed to precipitate exosomes, was calibrated for use on saliva collected from healthy individuals. The morphological and molecular features of the precipitations were compared with those obtained using the classical, physical-based method of ultracentrifugation (UC). ...

The discovery of disease-specific biomarkers in oral fluids has revealed a new dimension in molecular diagnostics. Recent studies have reported the mechanistic involvement of tumor cells derived mediators, such as exosomes, in the development of saliva-based mRNA biomarkers. To further ...

The cells continuously secrete a large number of different types of microvesicles including macro-and micro-molecules into the extracellular fluids. One of them are exosomes, which are nano-sized vesicles capable of transferring the DNAs, microRNAs, non-coding RNAs and lipids with or ...

from abcam.com Various secreted extracellular vesicles are present in urine, amniotic fluid, bronchoalveolar lavage fluid, breast milk, saliva and blood

There is an increasing interest in using microRNAs (miRNA) as biomarkers in autoimmune diseases. They are easily accessible in many body fluids but it is controversial if they are circulating freely or are encapsulated in microvesicles, particularly exosomes. Researchers at ...