Secreted vesicles have had a rather a mixed press in cancer biology. Originally considered as a ‘cellular trashcan’, with particular usefulness as a repository for specific proteins from the originating cell type, the literature now abounds with papers describing the ...
Read More »Characterization of secreted vesicles from vascular smooth muscle cells
The artery medial layer is mainly composed of vascular smooth muscle cells (VSMCs). These cells contribute to the formation of neointima and atherosclerotic plaques by switching from the quiescent-contractile to migratory-activated state. Apoptotic blebs, microvesicles and exosomes are secreted vesicles, ...
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