Engineered extracellular vesicles triggered a protective lipid response that reduced cytokine storm and inflammation in multiple mouse disease models...
Read More »Can bacterial extracellular vesicles break the blood-brain barrier?
Extracellular vesicles released by E. coli may contribute to blood-brain barrier damage in sepsis survivors, offering new insight into inflammation and the risk of neurological disease after infection...
Read More »Sepsis, or Death By Lethal Message
If scientists understand what causes this deadly cellular message chain, they might be able to stop it Like a poison pen, dying cells prick their neighbors with a lethal message. This may worsen sepsis...
Read More »Understanding the role of extracellular vesicles in neuroinflammation during sepsis
Sepsis is a severe medical condition that occurs when the body's response to infection leads to widespread inflammation. One concerning...
Read More »Extracellular vesicles as markers and mediators in sepsis
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. It remains a highly lethal condition in which current tools for early diagnosis and...
Read More »Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing
Extracellular vesicles (EVs) are intercellular communicators with key functions in physiological and pathological processes and have recently garnered interest because of their diagnostic and...
Read More »Exosome-derived miRNAs contribute significant information regarding sepsis diagnosis and survival prediction
Septic shock is a common medical condition with a mortality approaching 50% where early diagnosis and treatment are of particular importance for patient survival. Novel biomarkers that serve as prompt indicators of sepsis are urgently needed. High-throughput technologies assessing circulating ...
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