Exosomes are nanosized (50–150 nm) extracellular vesicles released by all types of cells in the body. They transport various biological molecules, such as DNAs, RNAs, proteins, and lipids from parent cells to recipient cells for intercellular communication. Exosomes, especially those ...
Read More »Nanoplasmonic Approaches for Sensitive Detection and Molecular Characterization of Extracellular Vesicles
All cells release a multitude of nanoscale extracellular vesicles (nEVs) into circulation, offering immense potential for new diagnostic strategies. Yet, clinical translation for nEVs remains a challenge due...
Read More »Nanoplasmonic sensors for detecting circulating cancer biomarkers – miRNA, ctDNA, exosomes and CTCs
The detection of cancer biomarkers represents an important aspect of cancer diagnosis and prognosis. Recently, the concept of liquid biopsy has been introduced whereby diagnosis and prognosis are...
Read More »Real time and label free profiling of clinically relevant exosomes
Tumor-derived exosomes possess significant clinical relevance due to their unique composition of genetic and protein material that is representative of the parent tumor. Specific isolation as well as identification of proportions of these clinically relevant exosomes (CREs) from biological samples ...
Read More »Label-free Quantitative Detection of Tumor-derived Exosomes through Surface Plasmon Resonance Imaging
Exosomes are endosome-derived membrane vesicles carrying proteins and nucleic acids that are involved in cellular functions such as intercellular communication, protein and RNA secretion, and antigen presentation, and therefore serve as potential biomarkers for many diseases including cancer. Since exosomes ...
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