More and more, scientists have realized that DNA is not the only way that a parent can pass on traits to their offspring. Events experienced by a parent over a lifetime can also have an impact. Now University of Pennsylvania ...
Read More »microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy
In response to stress, the heart undergoes extensive cardiac remodeling that results in cardiac fibrosis and pathological growth of cardiomyocytes (hypertrophy), which contribute to heart failure. Alterations in microRNA (miRNA) levels are associated with dysfunctional gene expression profiles associated with ...
Read More »Sorting it out: Regulation of exosome loading
Extracellular vesicles (EVs), a term that includes both exosomes of endocytic origin and vesicles derived from plasma membranes, are continuously secreted by cells to the extracellular environment, and represent a novel vehicle for cell-cell communication. Exosomes contain specific repertoires of ...
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