Exosomes are nanosized (50–150 nm) extracellular vesicles released by all types of cells in the body. They transport various biological molecules, such as DNAs, RNAs, proteins, and lipids from parent cells to recipient cells for intercellular communication. Exosomes, especially those ...
Read More »Direct quantification of cancerous exosomes via surface plasmon resonance with dual gold nanoparticle-assisted signal amplification
Sensitive detection of cancerous exosomes is critical to early diseases diagnosis and prognosis. Herein, a sensitive aptasensor was demonstrated for exosomes...
Read More »Analyses of intravesicular exosomal proteins using a nano-plasmonic system
Extracellular vesicles (EVs), including exosomes, are nanoscale membrane particles shed from cells and contain cellular proteins whose makeup could inform cancer diagnosis and treatment. Most analyses have focused on surface proteins while analysis of...
Read More »Nanoplasmonic sensors for detecting circulating cancer biomarkers – miRNA, ctDNA, exosomes and CTCs
The detection of cancer biomarkers represents an important aspect of cancer diagnosis and prognosis. Recently, the concept of liquid biopsy has been introduced whereby diagnosis and prognosis are...
Read More »Real time and label free profiling of clinically relevant exosomes
Tumor-derived exosomes possess significant clinical relevance due to their unique composition of genetic and protein material that is representative of the parent tumor. Specific isolation as well as identification of proportions of these clinically relevant exosomes (CREs) from biological samples ...
Read More »Molecular screening of cancer-derived exosomes by surface plasmon resonance (SPR) spectroscopy
Exosomes are nanovesicles shed by cells into their microenvironment and carry the molecular identity of their mother cells. These vesicles are actively involved in intercellular communication under physiological conditions and ultimately in the spread of various diseases such as cancer. ...
Read More »Label-free Quantitative Detection of Tumor-derived Exosomes through Surface Plasmon Resonance Imaging
Exosomes are endosome-derived membrane vesicles carrying proteins and nucleic acids that are involved in cellular functions such as intercellular communication, protein and RNA secretion, and antigen presentation, and therefore serve as potential biomarkers for many diseases including cancer. Since exosomes ...
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