Exosomes are extracellular nanovesicles that mediate a number of cellular processes, including intracellular signalling. There are many published examples of exosome-exosome dimers; however, their relevance has not been explored. Here, researchers from Ben-Gurion University of the Negev propose that cells ...
Read More »Detection and Characterization of Extracellular Vesicles by Transmission and Cryo-Transmission Electron Microscopy
Transmission electron microscopy (TEM) and transmission scanning electron Microscopy (TSEM), which denotes application of a scanning electron microscope (SEM) in the transmission mode, have been used to detect and characterize particles down to an imaging resolution of ~1 nm. In ...
Read More »Exosomes – improved methods to characterize their morphology, RNA content, and surface protein biomarkers
As a type of secreted membrane vesicle, exosomes are an emerging mode of cell-to-cell communication. Yet as exosome samples are commonly contaminated with other extracellular vesicles, the biological roles of exosomes in regulating immunity and promoting oncogenesis remain controversial. To ...
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