Exosomes are nanoscale membrane-derived vesicles that are secreted by cancer cells and play a critical role in modulating the tumor microenvironment and disease pathogenesis. Dsg2, a desmosomal cadherin often overexpressed in skin malignancies including squamous cell carcinoma (SCC), can activate ...
Read More »Expanding on Liquid Biopsies with Exosomes
A new type of liquid biopsy for solid tumors based on analyzing exosomes from the blood is being tested at Thomas Jefferson University. Thomas Jefferson University announces a partnership with Exosome Sciences Inc. to evaluate a novel liquid biopsy platform ...
Read More »Circulating Tumor Cells Provide Genomic Snapshot of Breast Cancer
Tumor cells isolated from the blood of patients with triple negative breast cancer reveal similar cancer-driving mutations as those detected from standard biopsy, suggesting that circulating cells could one day replace tissue biopsies The genetic fingerprint of a metastatic cancer ...
Read More »