Tumor associated macrophages (TAMs), which differentiate from circulating monocytes, are pervasive across human cancers and comprise heterogeneous populations. The contribution of tumor-derived signals to TAM heterogeneity is not well understood. In particular, tumors release both soluble factors and extracellular vesicles ...
Read More »Proteomic landscape of exosomes reveals the functional contributions of CD151 in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Patients with TNBC have poor overall survival due to limited molecular therapeutic targets. Recently, exosomes have...
Read More »Microfluidic human liver-chip to investigate the roles of breast cancer-derived extracellular vesicles
A new study, affiliated with UNIST has unveiled the mechanisms involved in the liver metastasis of breast cancer, thanks to the three-dimensional (3D) organ-on-a-chip that mimics human liver functions...
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