Sensitive and specific detection of tumor exosomes is of great significance for early cancer diagnosis. Researchers from Nanjing Normal University report an aptamer strategy for exosome detection based on aptamer recognition-induced multi-DNA release and cyclic enzymatic amplification. First, they use aptamer-magnetic bead ...
Read More »Exosome uptake by host cells is most promising for tailored exosomes as drug transporter
Exosomes (Exo), powerful intercellular communicators, are recovered in all body fluids, suggesting suitability for diagnosis and prognosis. Easy in vitro manipulation recommends Exo as drug vehicles. Aiming to consolidate diagnostic and therapeutic potential of Exo, researchers from the University Hospital of ...
Read More »Peregrine Licenses Novel Exosome-Based Cancer Detection and Monitoring Technology from UT Southwestern Medical Center
Peregrine Pharmaceuticals, Inc. (NASDAQ:PPHM) (NASDAQ:PPHMP), a biopharmaceutical company committed to improving patient lives by delivering high quality biological products through its contract development and manufacturing organization (CDMO) services and by advancing its novel R&D pipeline, today announced that the company ...
Read More »Postdoc position available – to understand the role of tumor exosomes in conditioning the metastatic niche
University of Minnesota, College of Veterinary Medicine, Veterinary Clinical Sciences Department A fully funded 2-year postdoctoral experience with the objective to understand the role of tumor exosomes in conditioning the metastatic niche is available in the laboratory of Dr. Jaime ...
Read More »More Evidence That Tumor Exosomes Pave the Way for Metastasis
from NEJM Watch by Anthony L. Komaroff An international team led by researchers at Weill Cornell Medicine, now reports that both mouse and human tumors that characteristically home to certain organs — lung, liver and brain — secrete exosomes that ...
Read More »Tests for Double-Stranded DNA Fragments in Exosomes Could Lead to Earlier, Easier Cancer Diagnoses and Targeted Treatments
DNA fragments packaged in tumor exosomes — small tumor-secreted vesicles — can be used to identify important genetic mutations in cancer, researchers at Weill Cornell have demonstrated. Because exosomes circulate in the blood, the discovery suggests that physicians could eventually ...
Read More »Metastasis formation may be hampered by tailored exosomes that outsmart tumor exosomes
Exosomes are small vesicles that derive from endosomes and are delivered by many cells, including tumor cells that are a particular rich source of exosomes. Exosomes are suggested to be the most potent intercellular communicators. Being recovered in all body ...
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