Extracellular vesicles help cancer cells communicate with surrounding stromal cells, and targeted protein degradation may disrupt this signaling network to suppress tumor growth...
Read More »Sungkyunkwan University, KIST researchers develop innovative anticancer platform
Targeted suppression of extracellular vesicles disrupted tumor-stroma communication, reprogrammed cancer-associated fibroblasts...
Read More »MetroHealth Scientist Awarded $3.3 Million NIH Grant to Study How Breast Cancer Spreads
MetroHealth Research Institute scientist Khalid Sossey-Alaoui, PhD, has been awarded a five-year, $3.3 million grant from the National Institutes of...
Read More »Orchestrating epigenetic and immune landscapes with multivalent mRNA-exosome vaccines
Engineered extracellular vesicles may improve mRNA cancer vaccine delivery while supporting targeted immune responses, tumor microenvironment remodeling, and personalized neoantigen-based...
Read More »Engineered extracellular vesicles could move beyond cargo delivery to reshape diseased tissue microenvironments
Engineered extracellular vesicles could extend therapeutic delivery beyond individual cells by coordinating changes across diseased tissue microenvironments through targeted cargo and...
Read More »Spatial-EV-seq provides a tissue map of extracellular vesicles
Spatial-EV-seq maps extracellular vesicles within intact tissues, revealing how their location and movement can shape immune activity and cellular communication in the tumor microenvironment...
Read More »Exosome proteins and microRNAs reveal shared patterns across cancers
Integrated profiling of proteins and microRNAs in cancer-derived exosomes reveals shared biological functions and cancer-specific patterns with...
Read More »T cells secrete DNA to help immune system fight cancer
Extracellular vesicles released by activated T cells transferred DNA to immune and tumor cells, enhancing antigen presentation and strengthening anti-tumor immune responses...
Read More »Extracellular vesicles deliver lncRNA signals that promote lung cancer metastasis
Extracellular vesicles deliver lncRNA ROLLCSC to lung cancer cells, reshaping lipid metabolism, suppressing ferroptosis, and promoting metastatic...
Read More »Plant-derived extracellular vesicles reshape the tumor microenvironment
Extracellular vesicles from plants show potential to remodel the tumor microenvironment, enabling targeted delivery and multipathway cancer therapy...
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