Ciloa is advancing a novel therapy by combining adiponectin with extracellular vesicles to treat type 2 diabetes and obesity, backed by €6.5 million in funding for clinical development and GMP manufacturing...
Read More »New mechanism behind vascular damage in type 2 diabetes identified
Researchers at Karolinska Institutet have found that extracellular vesicles from red blood cells contribute to blood vessel damage in type 2 diabetes. These vesicles transfer arginase-1, leading to oxidative stress and impaired vascular function. Blocking vesicle uptake and arginase activity could offer new therapeutic strategies for diabetes-related vascular...
Read More »Nanoliter plasma sample for disease diagnosis by using a visualization platform of counting extracellular vesicle particles
In recent years, scientists have been exploring innovative ways to diagnose diseases with minimal invasiveness, and extracellular vesicles (EVs) have emerged as a powerful tool in this field. EVs are tiny particles released by cells that carry important biological information, ...
Read More »A new horizon in drug delivery
An August 2024 publication by Assistant Professor of Health and Exercise Science, Dan Lark, showcases an innovative drug delivery approach for cancer and metabolic diseases, such as Type 2 diabetes and obesity. The approach relies on tiny particles...
Read More »Researchers report role of exosomes in breast cancer patients with obesity, diabetes
Obesity, insulin resistance and Type 2 diabetes are risk factors for breast cancer in post-menopausal women. The metabolic and inflammatory...
Read More »Extracellular vesicles and extracellular RNA in aging and age-related disease
Researchers at the National Institute on Aging have explored circulating markers of aging and an important age-related disease, type 2 diabetes mellitus. Their discovery of differences in exRNAs and EVs contributes to establishing a baseline reference...
Read More »Using exosomal microRNA to detect early signs of type 2 diabetes in teens
Researchers know that exosomes, tiny nanoparticles released from fat cells, travel through the bloodstream and body, regulating a variety of processes, from growth and development to metabolism. The exosomes are important in lean, healthy...
Read More »A step closer to a cure for adult-onset diabetes – could “sick” exosomes be to blame
In healthy people, exosomes – tiny structures secreted by cells to allow intercellular communication – prevent clumping of the protein that leads to type 2 diabetes. Exosomes in patients with the disease don’t have the same ability. This discovery by ...
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