Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and they perform as key regulators in cell-to-cell communication in normal as well as diseased...
Read More »Insights into the proteome of tumor-derived exosomes reveals new potential diagnostic biomarkers
Developing tumors continuously release nano-sized vesicles that represent circulating "fingerprints" of the tumor's identity. In gastrointestinal stromal tumor (GIST), University of Kansas Medical Center...
Read More »Exosomes – new molecular targets of diseases
Extracellular vesicles (EVs) comprise apoptotic bodies, microvesicles and exosomes, and they perform as key regulators in cell-to-cell communication in normal as well as diseased...
Read More »Characterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid
Exosomes and microvesicles (i.e., extracellular vesicles: EVs) have been identified within ovarian follicular fluid and recent evidence suggests that EVs are able to elicit profound effects on ovarian cell function. While existence of miRNA within EVs has been reported, whether ...
Read More »Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
Developing blood-based tests is appealing for non-invasive disease diagnosis, especially when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes have attracted increasing interest in non-invasive cancer diagnosis and monitoring of treatment response. However, the biology and ...
Read More »Said the tumor to its neighbor, “You’ve got mail”
By Alissa Poh Cells have their own miniaturized postal service in the shape of vesicles, or tiny bubbles through which molecules crucial for biological processes like communication and food intake are sorted, packaged and delivered. Aside from the 2013 Nobel ...
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