Macrophages are key participants in melanoma growth and survival. In general, macrophages can be classified as M1 or M2 activation phenotypes. Increasing evidence demonstrates that melanoma exosomes also facilitate tumor survival and metastasis. However, the role of melanoma exosomes in ...
Read More »MVP-mediated selective sorting of tumour suppressor miRNA into exosomes promotes tumour progression
Exosomes are emerging mediators of intercellular communication; whether the release of exosomes has an effect on the exosome donor cells in addition to the recipient cells has not been investigated to any extent. Here, researchers from the University of Louisville ...
Read More »Exosomal miRNAs as biomarkers of recurrent lung cancer
Prognosis of lung cancer still remains grim largely due to recurrence and aggressive metastasis of the disease. In this study, researchers from the University of Louisville examined the potential of exosomal miRNAs as biomarkers of recurrent lung cancer. Initially, in ...
Read More »Interspecies communication through edible plant derived exosome-like nanoparticles
Exosomes, small vesicles participating in intercellular communication, have been extensively studied recently; however, the role of edible plant derived exosomes in interspecies communication has not been investigated. Here, researchers from the University of Louisville investigate the biological effects of edible ...
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