Tag Archives: University of North Carolina at Chapel Hill

There are many confounding factors related to HIV, including how the virus is able to remain dormant and reactivate in the absence of antiretroviral drugs. Once these aspects of the virus are mapped out, researchers stand a better chance of ...

Exosomes have recently emerged as a promising drug delivery system with low immunogenicity, high biocompatibility, and high efficacy of delivery. Researchers at University of North Carolina at Chapel Hill demonstrated earlier that macrophage-derived exosomes (exo) loaded with a potent anticancer ...

The release of membrane-bound vesicles from cells is being increasingly recognized as a mechanism of intercellular communication. Extracellular vesicles (EVs) or exosomes are produced by virus-infected cells and are thought to be involved in intercellular communication between infected and uninfected ...

Cancer drugs packaged in immune bubbles home in directly to tumors without getting sidetracked and destroyed; less chemo with better results Chapel Hill, N.C. – (Jan.14, 2016) —The cancer drug paclitaxel just got more effective. For the first time, researchers ...

Exosomes have recently come into focus as “natural nanoparticles” for use as drug delivery vehicles. Researchers at the University of North Carolina at Chapel Hill set out to assess the feasibility of an exosome-based drug delivery platform for a potent ...

Exosomes are naturally occurring nanosized vesicles that have attracted considerable attention as drug delivery vehicles in the past few years. Exosomes are comprised of natural lipid bilayers with the abundance of adhesive proteins that readily interact with cellular membranes. Researchers ...

Circulating microRNAs (miRNAs), such as those found in exosomes, have emerged as diagnostic tools and hold promise as minimally invasive, stable biomarkers. Transfer of tumor-derived exosomal miRNAs to surrounding cells may be an important form of cellular communication. Kaposi’s sarcoma-associated ...