Researchers have created an inhalable COVID-19 vaccine that is shelf stable at room temperature for up to three months, targets the lungs specifically and effectively, and allows for self-administration via an inhaler. The researchers also found that the delivery mechanism ...
Read More »A vaccine formulated with Chlamydia exosomes elicits protection against a respiratory challenge
Researchers at the University of California, Irvine set out to determine if exosomes, isolated from Chlamydia muridarum infected HeLa cells (C. muridarum-exosomes), induce protective immune...
Read More »Boosting cancer vaccines with extracellular vesicle-internalizing receptors
Researchers at EPFL have created artificial molecules that can help the immune system to recognize and attack cancer tumors. The study is published in...
Read More »Purification of virus-like particles and separation of other extracellular particles
Enveloped virus-like particles (VLPs) are increasingly used as vaccines and immunotherapeutics. Frequently, very time consuming density gradient centrifugation techniques are used for purification of VLPs. However, the progress towards optimized large-scale VLP production increased the demand for fast, cost efficient ...
Read More »Frontiers Publishing Establishes Research Topic – Exosome Functions in Infectious Diseases
About this Research Topic Exosomes have recently been classified as the newest family members of ‘bioactive vesicles’ that function to promote intercellular communication. These microvesicles originate from the late endosomes and are released into the extracellular milieu through multivesicular body ...
Read More »Targeting soluble proteins to exosomes using a ubiquitin tag
As “natural” antigen carriers in the body, exosomes are potential vaccine vectors. A number of animal studies indicate that antigen-containing exosomes can induce a specific immune response which can protect against tumor progression or various infections. Exosomes that carry the ...
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