Tag Archives: vesicles

Ras and exosome signaling

exosomes

Ras gene (HRAS, NRAS, and KRAS) has been observed to be mutated and hyper-activated in a significant proportion of cancers. However, mutant Ras remains a challenging therapeutic target. Similarly, inhibition of targets upstream and downstream of Ras has shown limited ...

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Vesicle vehicles of genetic information

exosome rna

from Nature Reviews Genetics Exosomes are a type of extracellular vesicle that can transfer cellular cargo between cells and have emerging importance in cell–cell communication. The exosome-mediated transfer of genetic information in the form of microRNAs (miRNAs) or mRNAs has ...

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Microvesicles and exosomes for intracardiac communication

exosome rna

The heart is an organ with a complex mixture of well-organized interactions of different cell types that facilitate proper myocardial contractility, sufficient perfusion, balanced myocardial extracellular stiffness, and controlled functioning of the immune system. Several cell types, including cardiomyocytes, endothelial ...

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Exploration of microRNAs in porcine milk exosomes

exosomes

Breast milk contains complex nutrients and facilitates the maturation of various biological systems in infants. Exosomes, membranous vesicles of endocytic origin found in different body fluids such as milk, can mediate intercellular communication. Researchers at the South China Agricultural University hypothesized ...

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