Extracellular vesicles (EVs) play an important role in intercellular communication. They are naturally released from cells into the extracellular environment. Based on their biogenesis, release pathways, size, content, and function, EVs are classified into exosomes, microvesicles (MVs), and apoptotic bodies ...
Read More »Post-doc position available – EVs in wound healing and tissue regeneration biology
We are searching for a full-time post-doctoral fellow in the Hansjörg Wyss Department of Plastic Surgery at the New York University Langone Medical Center...
Read More »First Dosing in Exopharm’s PLEXOVAL Exosome Wound Healing Human Study
Regenerative medicine company Exopharm Limited (ASX:EX1) announces first dosing has occurred in the PLEXOVAL Phase I study using exosomes...
Read More »Scientists have created an electronic wafer that can reprogram exosomes
NPR – by Angus Chen – Scientists have created an electronic wafer that reprogrammed damaged skin cells on a mouse’s leg to grow new blood vessels and help a wound heal. One day, creator Chandan Sen hopes, it could be ...
Read More »Exosome-based biologic drug APOSEC offers possible new treatments for dermal wounds
APOSEC is a substance obtained from white blood corpuscles and was developed by a research group led by thoracic surgeon Hendrik Jan Ankersmit, Head of the Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration at MedUni Vienna . ...
Read More »Stem cell exosomes in wound dressings promote healing
There is a need to find better strategies to promote wound healing, especially of chronic wounds, which remain a challenge. Researchers from Shanghai Jiao Tong University found that synovium mesenchymal stem cells (SMSCs) have the ability to strongly promote cell proliferation ...
Read More »Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds
Chronic wounds have become an economic, social, and public health burden and need advanced treatment. Platelet-rich plasma (PRP) has been used extensively in treatment of chronic wounds because it contains an abundance of growth factors secreted by platelets. The exosomes ...
Read More »The Exosome – A Naturally Secreted Nanoparticle and its Application to Wound Healing
Wound healing is a complex process and often delayed in patients with underlying chronic conditions. The cost of wound care is a significant burden to the society, warranting new techniques to prompt wound healing. Several studies have reported on the ...
Read More »Upcoming Clinical Trial – Effect of Plasma Derived Exosomes on Cutaneous Wound Healing
ClinicalTrials.gov Identifier: NCT02565264 Sponsor: Kumamoto University Purpose This study is an open prospective clinical trial. The objective is to evaluate the effect of autologous exosomes rich plasma on cutaneous wound healing. The participants are patients with intractable cutaneous ulcers (e.g. ...
Read More »Microvesicles are ubiquitous contributors to infection and immunity
MVs, which can be subgrouped into exosomes, SVs, and OMVs, are secreted by eukaryotic and prokaryotic cells. Many previously inexplicable phenomena can be explained by the existence of these vesicles, as they appear to be important in a wide range ...
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