Join the audience for a live webinar at 3 p.m. GMT/10 a.m. EST on 29 November 2023 exploring exosomes and the development of different sensing platforms for detection using nanoparticle integrated plasmonic platforms
Exosomes are a class of extracellular vesicles (EVs) that are unique nano-sized cargo-bearing biological vesicles, secreted by almost all normal and cancer cells into the extracellular space. These are the smallest of extracellular vesicles (in the range of 30–150 nm) present in all body fluids, making them suitable for liquid biopsy.
This webinar covers an introduction to exosomes and the development of different sensing platforms for detection using nanoparticle integrated plasmonic platforms. Platforms include nanometal-polymer composite films integrated with inorganic nanoparticles dispersed into a polymer matrix. Nanoparticles such as gold and silver are used for their strong localized surface plasmon resonance in visible spectrum, which originates from the excitation of plasmons by incident light. This property makes noble metal-polymer nanocomposites particularly adequate for sensing and biosensing applications. Furthermore, association of Au and Ag nanoparticles of various shapes with poly(dimethyl siloxane) (PDMS), allows the use of nanocomposite materials for microfluidic-based biosensing as well.
Also included is a discussion of the in situ synthesis of nano-PDMS nanocomposites both at the macroscale and inside the channel of a microfluidic chip. The nanocomposite has been used successfully for sensing different biological entities including exosomes. Breast-cancer detection using exosomes in lab-on-chips is demonstrated.
An interactive Q&A session follows the presentation.LEARN MORE