WO2021033990 – Composition Comprising Exosomes Derived from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cell Precursor for Prevention or Treatment of Non-Alcoholic Steatohepatitis

The present invention relates to a pharmaceutical composition for prevention or treatment of non-alcoholic steatohepatitis, the composition comprising, as an active ingredient, exosomes isolated from induced pluripotent stem cell-derived mesenchymal stem cells which have been or have not been treated with a pretreatment material. The exosomes of the present invention exhibit a more improved effect of preventing or treating non-alcoholic steatohepatitis, compared to those isolated from conventional mesenchymal stem cells and as such, can be advantageously used for relevant research and development and productization.


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