Tag Archives: intercellular signaling

Large extracellular vesicles help cells communicate, remove cellular waste, and maintain tissue health while offering promising opportunities for disease diagnosis and targeted therapies...

Growing interest in extracellular vesicles and exosomes highlights their potential as drug delivery vehicles, biomarkers, and regulators of cell communication across medicine, biotechnology...

Extracellular vesicles and newly discovered nanoparticles like supermeres reveal a complex and evolving system of intercellular communication...

Extracellular vesicles are cell-derived messengers that transfer proteins, lipids, and RNA, playing key roles in cell communication, disease processes, and emerging clinical applications...

RNA-binding proteins like human antigen R (HuR) are key regulators in post-transcriptional control of gene expression in several pathophysiological conditions. Diabetes adversely affects monocyte/macrophage biology and function. It is not known whether diabetic milieu affects cellular/exosome-HuR and its...

Metastasis in cancer consists of multiple steps, including epithelial-mesenchymal-transition (EMT), which is characterized by the loss of epithelial-like characteristics and the gain of mesenchymal-like attributes including cell migration and invasion. It is clear that the tumor microenvironment can promote the ...

Mesenchymal stem cells (MSCs), whose mechanism of action is predominantly paracrine, are being widely tested for the treatment of a variety of human diseases. No one factor has been proven sufficient to mediate the therapeutic effects of MSCs. However, exosomes-membrane ...

Extracellular vesicles, in particular exosomes, have gained much attention as potent mediators of intercellular signaling. Exosomes are 50-130 nm intraluminal vesicles of multivesicular bodies (MVB) that are secreted into the extracellular environment upon fusion of MVB with the plasma membrane. ...