Mesenchymal stem cell-derived extracellular vesicles improved post-stroke recovery in rats, with stronger benefits in females linked to interactions with...
Read More »Engineering minimal extracellular vesicle mimetics to decode surface protein function
A cell-free platform engineers artificial extracellular vesicles to systematically test how individual surface proteins control uptake and function, advancing...
Read More »“See-and-treat” solution for stroke via quantum dot-engineered extracellular vesicles
Engineered extracellular vesicles enable real-time imaging and therapy in ischemic stroke, combining exosomes with quantum dots to protect the brain...
Read More »Intranasal delivery of stem cell-derived extracellular vesicles offers new hope for Alzheimer’s disease
Intranasal delivery of mesenchymal stem cell-derived extracellular vesicles reduced brain inflammation and improved neuron connectivity in an Alzheimer’s model, suggesting a promising noninvasive therapeutic approach for neuroprotection and immune...
Read More »NSCs-derived extracellular vesicles exhibit neuroprotective effect in Parkinson’s disease models
Extracellular vesicles derived from neural stem cells show strong neuroprotective effects in Parkinson’s disease models. This study reveals that NSC-EVs, enriched with the antioxidant enzyme Catalase, can reduce oxidative stress, enhance neuron survival...
Read More »Exosomes: the insulin of our era?
Miller School experts discussed the potential biomarker and therapeutic value of exosomes. Initially believed to be a mechanism for cells to “take out the trash,” the latest research in the exosome field indicates that minute, extracellular vesicles released by all ...
Read More »Exploring extracellular vesicles from bovine colostrum as a promising therapy for Parkinson’s disease
An unconventional collaboration between UNMC researchers and an Elmwood, Nebraska, farm family has led to a possible new therapy for Parkinson’s disease. Extracellular vesicles from bovine colostrum...
Read More »Neural stem cell derived extracellular vesicles – attributes and prospects for treating neurodegenerative disorders
Neural stem cell (NSC) grafting in conditions such as aging, brain injury, and neurodegenerative diseases promotes regeneration, plasticity and functional recovery. Recent studies have revealed that...
Read More »Exosomes as a potential novel therapeutic tools against neurodegenerative diseases
Exosomes are extracellular vesicles that can transfer biological information over long distances affecting normal and pathological processes throughout organism. It is known that very often composition and therapeutic properties of exosomes depends on cell type and its physiological state. Thus, ...
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